COVID-19 vaccine hesitancy: A Systematic review of cognitive determinants

Sara Pourrazavi ^1,2 , Zahra Fathifar ³, Manoj Sharma ^4,5 , Hamid Allahverdipour ^1,2 *

Cited by CrossRef: 12

1- Rubin M, Birkhead D, Mogrovejo B, Stephens A, Gordon L. Childhood COVID-19 Vaccine Poster Project: A Resident-Led Advocacy Campaign. 2025; [Crossref]

2- Pelletier C, Gagnon D, Dubé E, Kampadilemba O. “It’s not that I don’t trust vaccines, I just don’t think I need them”: Perspectives on COVID-19 vaccination. PLoS ONE. 2024;19(2):e0293643 [Crossref]

3- Ranjbaran S, Chollou K, Pourrazavi S, Babazadeh T. Barriers to COVID-19 vaccine uptake: classification and the role of Health Literacy and Media Literacy. Front Public Health. 2023;11 [Crossref]

4- Voloshin A, Altermatt A, Wilkinson A, Gibney K, Hill S, Kaufman J, Ryan R, Danchin M, Pedrana A, Hellard M, Heath K. What Drives Vaccine Uptake?—Investigating the Application of the Health Belief Model Through a Longitudinal Cohort Study During the COVID-19 Pandemic in Victoria, Australia. Vaccines. 2025;13(10):1021 [Crossref]

5- Htet H, Wichaidit W, Chuaychai A, Sottiyotin T, Htet K, Sriplung H, Chongsuvivatwong V, Show K. Perspectives of stakeholders on barriers to COVID-19 protective behaviors adherence and vaccination among Myanmar migrant workers in southern Thailand: A qualitative study. PLoS ONE. 2025;20(3):e0317714 [Crossref]

6- Zaino A, Bonacquisti M, Russo L, Sabetta T, Solipaca A, Ricciardi W, Boccia S, Villani L. Influenza vaccination coverages in Italy from 1999/00 to 2023/24: A joinpoint regression analysis. Journal of Infection and Public Health. 2025;18(10):102875 [Crossref]

7- E, Matondo A, Ngbolua K, Mpiana P. Evaluation of antiviral potential of Cinchona officinalis derived compounds against COVID-19 and human hepatitis B: An in silico molecular docking and molecular dynamics simulation study. Pharmacological Research - Natural Products. 2025;7:100229 [Crossref]

8- Wiesmann C, Conway B. The challenge of normalizing vaccine behaviors in the postpandemic era. 2025;39(2):206 [Crossref]

9- Isonne C, Marzuillo C, Villari P, Baccolini V. The role of vaccine literacy and health literacy in the health prevention decision-making process. Human Vaccines & Immunotherapeutics. 2024;20(1) [Crossref]

10- Fabbri L, Stanel S. New Evidence for SARS-CoV-2 Vaccine Boosting in Patients With Chronic Lung Diseases. CHEST. 2024;166(4):655 [Crossref]

11- Ittefaq M, Vu H, Zain A, Ramazan T, Kreps G. Analysis of public opinion polls about COVID-19 vaccines: Theoretical and policy implications for vaccine communication and campaigns to address vaccine hesitancy. Human Vaccines & Immunotherapeutics. 2024;20(1) [Crossref]

12- Connolly S, Liebermann E, Greaney M, Cohen S, Lindsey H, Prue O, Keller J. “They were saying that it’s the end of the world”: Experiences of COVID-19 and beliefs about the COVID-19 vaccine among refugees in Rhode Island, US. Human Vaccines & Immunotherapeutics. 2025;21(1) [Crossref]

13- Brusaferro S, Brunelli L, Arnoldo L, Arzilli G, Sangiovanni-Vincentelli A, Privitera G. Microwave irradiation for airborne virus inactivation: Evidence and future perspectives. Journal of Infection. 2025;91(2):106537 [Crossref]

14- Moreira da Cunha N, Tzirita S, Gobbo E, Herzig van Wees S. Factors influencing adolescents’ decision-making about COVID-19 vaccination: a systematic review with qualitative synthesis. Front Public Health. 2025;13 [Crossref]

15- Lubej M, Kirbiš A. Why does health literacy matter, and for whom? Explaining the differentiating impact of health literacy on vaccine attitudes. Front Psychol. 2025;16 [Crossref]

16- Roy D, Rashid M, Aktar A, Parvin M, Islam M. Potential predictors of COVID-19 booster vaccine confidence among adult people: a cross-sectional analysis amid the Omicron surge in Southern Bangladesh. Vaccine. 2025;64:127693 [Crossref]

17- Sangeetha M, Menon P, Kharmawphlang B, Shivashankarappa D, Nagaraja S. COVID-19 Vaccine Hesitancy among Adults in India: A Systematic Review and Meta-analysis. 2024;68(4):534 [Crossref]

18- Wong L, Alias H, Lee H, Zhao Q, Huang Z, Hu Z, Lin Y, Bowen R. Investigating post-COVID-19 confidence in emergency use authorization vaccines: A hypothetical case of mpox. PLoS Negl Trop Dis. 2025;19(5):e0013037 [Crossref]

19- Yang K, Jiang S, Jiang J. Influencing factors of influenza vaccination willingness among the elderly in Wuxi city: A study based on the Behavioral and Social Drivers (BeSD) framework and structural equation modeling. Human Vaccines & Immunotherapeutics. 2025;21(1) [Crossref]

20- Ohno M, Sekiya T, Obeng-Kyeremeh R, Handabile C, Haruta M, Nomura N, Kawakita T, Shingai M, Kida H. Optimization of the preparation method of inactivated intact virus particle vaccine for COVID-19. Vaccine. 2025;56:127173 [Crossref]

21- Fasce A, Mustață M, Deliu A, Holford D, Karlsson L, Gould V, Dumitra G, Farcasanu D, Vișinescu I, Verger P, Lewandowsky S. A field test of empathetic refutational and motivational interviewing to address vaccine hesitancy among patients. npj Vaccines. 2025;10(1) [Crossref]

22- Lee A, Sheppard M, Naughtin C, Rebuli M, Brindal E. Key Predictors that Characterize Different Stances on Significant Global Scientific Challenges: Comparing Vaccine and Climate Change Beliefs. SAGE Open. 2025;15(1) [Crossref]

23- Saha T, Masum Z, Biswas A, Mou M, Ahmed S, Saha T. Inhaled Dry Powder of Antiviral Agents: A Promising Approach to Treating Respiratory Viral Pathogens. Viruses. 2025;17(2):252 [Crossref]

24- Budd E, De Anda S, Halvorson S, Leve L, Mauricio A, McWhirter E, García J, DeGarmo D. Social Determinants of Health Associated With SARS-CoV-2 Testing and Vaccine Attitudes in a Cross-Sectional Study of Latinx Individuals in Oregon. AJPM Focus. 2025;4(3):100326 [Crossref]

25- Grygarová D, Kožený J, Tišanská L, Havlík M, Horáček J. Trust in official information as a key predictor of COVID-19 vaccine acceptance: evidence from a Czech longitudinal survey study. BMC Public Health. 2025;25(1) [Crossref]

26- Chen A, Anthony A, Balogun A, Pereira R, Cole J. The Impact of Motivational Interviewing and MOTIVE Tool Use by Pharmacists on Vaccine Acceptance. Pharmacy. 2024;12(4):114 [Crossref]

27- Pepino C, Malerba F, Biagioli V, D’Ambrosio T, Zampatti N, Canzoneri F, Ferro J, Crocco M. SARS-CoV-2 Vaccination Coverage in Italian Children with Celiac Disease. JCM. 2024;13(19):5851 [Crossref]

28- Kimmig C, Langer T, Loy J, Bender S, Haddad A. Children and adolescents’ experiences of mandatory SARS-CoV-2 testing in schools: a cross-sectional survey. bmjpo. 2024;8(1):e002974 [Crossref]

29- Sadat Larijani M, Bavand A, Banifazl M, Ashrafian F, Moradi L, Ramezani A. Determination of COVID-19 Late Disorders as Possible Long-COVID and/or Vaccination Consequences. J Prim Care Community Health. 2024;15 [Crossref]

30- Kim Y, Iachan R, Boyle J, Deng Y. Association Between County-Level Social Vulnerability and Vaccine-Related Attitudes and Hesitancy Toward COVID-19 Vaccination in the United States. Vaccines. 2024;12(12):1368 [Crossref]

31- Comacchio C, Cesco M, Martinelli R, Garzitto M, Bianchi R, Innocente N, Sozio E, Tascini C, Balestrieri M, Colizzi M. Psychological factors associated with vaccination hesitancy: an observational study of patients hospitalized for COVID-19 in a later phase of the pandemic in Italy. Front Psychiatry. 2023;14 [Crossref]

32- Varshney K, Skakic I, Ghosh P, Raj M, Shet D. International Patterns in Public Perceptions and Hesitancy Towards a Combined COVID-19 and Influenza Vaccination: A Scoping Review of Five Studies. COVID. 2025;5(7):103 [Crossref]

33- Castilla-Torres N, Castilla J, Sal y Rosas V, Tinco J, Medina J, Vega C. Eventos adversos y nivel de alfabetización en salud como barreras de vacunación infantil en Perú. Vacunas. 2025;:500488 [Crossref]

34- Vu M, Yeom J, Trinh D, Gou J, Hong T, Zaheeruddin M, Bishop-Royse J, Hartstein M, Spring B, Moskowitz D, Doan A, Martin M. A Latent Class Analysis of COVID-19 Vaccine Attitudes and Beliefs: Results from a Community Survey Conducted Via the Chicagoland Community Engagement Alliance (CEAL) Program. J Community Health. 2025;50(5):883 [Crossref]

35- Kura K, Abubakar R. Dataset on a reliability generalization meta-analysis of the Oxford COVID-19 vaccine hesitancy scale. Data in Brief. 2024;54:110451 [Crossref]

36- Bulilan E, Uyheng J, Montiel C. Multilayered politicized constructions of COVID-19 vaccines: A global south view of Pfizer and Sinovac. J Soc Polit Psych. 2024;12(2):173 [Crossref]

37- Iannizzi C, Andreas M, Bohndorf E, Hirsch C, Zorger A, Brinkmann-Paulukat J, Bormann B, Kaufman J, Lischetzki T, Monsef I, Neufeind J, Schmid-Küpke N, Thole S, Worbes K, Skoetz N. Communication-based interventions to increase COVID-19 vaccine willingness and uptake: a systematic review with meta-analysis. BMJ Open. 2025;15(5):e072942 [Crossref]

38- Kumru G, Akdemir İ, Demir C, Ates K, Erturk S, Nergizoglu G, Keven K, Kutlay S, Sengul S. Indicators of vaccination status in patients with chronic kidney disease: the importance of recommendations from healthcare providers. BMC Nephrol. 2025;26(1) [Crossref]

39- Richman A, Schwartz A, Torres E, Wu Q. Predictors of COVID-19 vaccine recommendation practices among healthcare providers in the US. Patient Education and Counseling. 2025;134:108687 [Crossref]

40- Gilliland K, Kilinsky A. Vaccine Hesitancy: Where Are We Now?. Pediatr Ann. 2025;54(5) [Crossref]

41- Elbers S, Vaughan D, Tiruneh Y. COVID-19 Vaccine Motivation and Hesitancy among a Sample of African American, Afro-Caribbean, and African Respondents in the United States. Vaccines. 2024;12(6):571 [Crossref]

42- Saha A, Ghosh Roy S, Dwivedi R, Tripathi P, Kumar K, Nambiar S, Pathak R. Beyond the Pandemic Era: Recent Advances and Efficacy of SARS-CoV-2 Vaccines Against Emerging Variants of Concern. Vaccines. 2025;13(4):424 [Crossref]