Opium dependence and the potential impact of changes in treatment coverage level: A dynamic modeling study

Hosein Rafiemanesh ¹ , Afarin Rahimi-Movaghar ² , Ali Akbar Haghdoost ^3,4 , Alireza Noroozi ² , Jaleh Gholami ² , Bita Vahdani ⁵ , Amin Afshar ^6,2, Mohammad Salehi ⁶, Koorosh Etemad ¹ *

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1- Nemati A, Raouf-Rahmati A, Serhan H, Mashreghi A, DadgarMoghaddam M, Hakim H, Talebi M, Ahmadi R, Niroumand S. Comparing quality of life methadone and buprenorphine for opioid substitution treatment in Iran. Sci Rep. 2025;15(1) [Crossref]

2- Tavakoli T, Taghizadeh kashani L, Shirzad M, Memarzadeh M, Shamsizadeh A, Kaeidi A, Hassanshahi J, Hassanipour M. Effect of a traditional herbal formulation (Azaraghi Majoon) on opium use disorder in male rats. ADV TRADIT MED (ADTM). 2024;24(4):1215 [Crossref]

3- Spence C, Kurz M, Sharkey T, Miller B. Scoping Literature Review of Disease Modeling of the Opioid Crisis. Journal of Psychoactive Drugs. 2025;57(3):333 [Crossref]