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Health Promot Perspect. 2026;16(3): 459-468.
doi: 10.34172/hpp.45878
  Abstract View: 16
  PDF Download: 5

Original Article

Urban Family Physician Program and Out-of-Pocket Health Expenditures in Iran: A Quasi-Experimental Interrupted Time Series and Difference-in-Difference Analysis, 2002-2020

Seyede-Fereshte Hosseini 1 ORCID logo, Ali Imani 1,2, Farhad Lotfi 3,4, Behzad Najafi 1* ORCID logo

1 Health Economics Department, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran
2 Tabriz Health Services Management Research Center, Health Management and Safety Promotion Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
3 Health Human Research center, School of Health Management and Information Sciences, Shiraz University of Medical Sciences, Shiraz, IR,Iran
4 National Center For Health Insurance Research, Tehran, IR, Iran
*Corresponding Author: Behzad Najafi, Email: bnadjafi59@gmail.com

Abstract

Introduction: Out-of-pocket (OOP) payment is an key indicator of financial burden in health. We assessed changes in per-capita OOP expenditures associated with Iran’s Urban Family Physician Program (UFPP), implemented in Fars and Mazandaran provinces in 2012, compared with aggregated non-intervention provinces.

Methods: We conducted a quasi-experimental policy evaluation with difference-in-differences (DID) and interrupted time series (ITS) analyses using Statistical Center of Iran data for 2002–2020. Fars and Mazandaran were the intervention provinces; while the remaining provinces constituted the aggregated non-intervention comparison group. The outcome was annual per-capita household OOP expenditure at constant 2020 prices. DID estimated changes relative to the comparison series, while ITS estimated immediate level and post-intervention trend changes. Inference was based on Newey–West HAC standard errors.

Results: In Fars, DID analysis indicate a significant decrease in per-capita OOP expenditures relative to the aggregated non-intervention comparison series (β3=−5,981; CI, −11,400 to −595; P=0.031). ITS showed a significant immediate level reduction (β6=−9,242; CI, −16,800 to -1.712; P=0.016), with no significantly change in trend (β7=−1,278; CI -2.623 to 68; P=0.063). In Mazandaran, no significant change was observed in aggregate OOP expenditures; however, service-specific analyses revealed heterogeneous changes across expenditure categories.

Conclusion: UFPP implementation was associated with an immediate reduction in per-capita OOP expenditures, without a significant trend change in Fars and no significant aggregate change was observed in Mazandaran.


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Submitted: 26 Apr 2026
Revision: 11 Aug 2026
Accepted: 07 Sep 2026
ePublished: 05 Nov 2026
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