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Submitted: 28 Sep 2019
Accepted: 26 Oct 2019
ePublished: 30 Mar 2020
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Health Promot Perspect. 2020;10(2): 98-115.
doi: 10.34172/hpp.2020.18
PMID: 32296622
PMCID: PMC7146037
  Abstract View: 272
  PDF Download: 236
  Full Text View: 74

Systematic Review

Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis

Majid Mobasseri 1 ORCID logo, Masoud Shirmohammadi 2, Tarlan Amiri 3, Nafiseh Vahed 4,5, Hossein Hosseini Fard 5, Morteza Ghojazadeh 5 * ORCID logo

1 Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3 Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
4 Emergency Medicine Research Team, Tabriz University of Medical Sciences, Tabriz, Iran
5 Research Center for Evidence-Based Medicine, Iranian EBM Centre: A Joanna Briggs Institute Affiliated Group, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Background: Diabetes is referred to a group of diseases characterized by high glucose levels in blood. It is caused by a deficiency in the production or function of insulin or both, which can occur because of different reasons, resulting in protein and lipid metabolic disorders. The aim of this study was to systematically review the prevalence and incidence of type 1 diabetes in the world.

Methods: A systematic search of resources was conducted to investigate the prevalence and incidence of type 1 diabetes in the world. The databases of Medline (via PubMed and Ovid),ProQuest, Scopus, and Web of Science from January 1980 to September 2019 were searched to locate English articles. The located articles were screened in multiple levels of title, abstract,and full-text and final studies that met the inclusion criteria were retrieved and included in the study.

Results: From 1202 located articles, 193 studies were included in this systematic review. The results of meta-analysis showed that the incidence of type 1 diabetes was 15 per 100,000 people and the prevalence was 9.5% (95% CI: 0.07 to 0.12) in the world, which was statistically significant.

Conclusion: According to the results, the incidence and prevalence of type 1 diabetes are increasing in the world. As a result, insulin will be difficult to access and afford, especially in underdeveloped and developing countries.

Keywords: Diabetes mellitus, Incidence, Prevalence, Systematic review, Type 1, World
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Abstract View: 272

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Full Text View: 74

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