Tabriz University of Medical Sciences Health Promotion Perspectives 2228-6497 7 2 2017 03 05 Safe sex self-efficacy and safe sex practice in a Southern United States College 74 79 10.15171/hpp.2017.14 EN Ovuokerie Addoh Eveleen Sng Paul D. Loprinzi Journal Article 10.15171/hpp.2017.14 2016 08 17 2016 12 18 Background: The purpose of this study was to assess the association between safe sex self-efficacy and safe-sex practice in a Southern college setting. Methods: Multivariable logistic regression models were used to examine the association between safe sex self-efficacy in four domains (mechanics, partner disapproval, assertiveness, intoxicants) and safe sex practice (outcome variable). Results: For every 1-unit increase in the composite condom use self-efficacy score, there was an 8% increase in the odds of being beyond the median safe-sex practice score (odds ration [OR]: 1.08, 95% CI: 1.02-1.15). Additionally, for every 1-unit increase in intoxicants self-efficacy score, there was a 31% increase in the odds of being beyond the median safe-sex practice score (OR: 1.31, 95% CI: 1.08-1.58). Conclusion: A greater degree of safe-sex self-efficacy is associated with increased odds of safe-sex practice. These findings are informative for the development of targeted approaches to foster safe-sex behavior in Southern US colleges.